Some authors [17] have also associated AFC and ovarian volume (OV) and have further negatively correlated AFC and OV with age, indicating that ovarian follicles decreased with increase in age.This prospective study was designed to investigate the relationship between Anti-Müllerian hormone (AMH) levels and ovarian volume (OV) and to determine whether these markers of ovarian reserve correlate with serum androgen levels and years since menarche (gynecological age) in women with PCOS versus normo-ovulatory women. The gene discussed is AMH; the disease is polycystic ovary syndrome.