ALS2CL and head and neck squamous cell carcinoma: Our microarray analysis also showed that some other genes were known to be associated with other T-leukemia sub-types or cancer as Irf4 (an oncogene locus which is frequently translocated in peripheral T-cell lymphomas) [7], Depdc6 (when over-expressed, it increases survival of hepatocellular carcinoma cells) [9] and Als2cl (a tumor-suppressor gene that contributes to the tumorigenesis of head and neck squamous cell carcinoma) [10].