Normotensive ADPKD patients with preserved renal function show significantly increased serum levels of vascular inflammatory markers: intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule-1 (VCAM-1), P-selectin, E-selectin and soluble Fas (sFas) as compared to healthy controls [25,26]. Here, SELP is linked to autosomal dominant polycystic kidney disease.