When DJ-1 was analyzed as a possible prognostic factor in each grade of the studied astrocytomas, the Kaplan- Meier analysis proved that the anaplastic astrocytomas showing score 3 DJ-1 were associated with shorter survival (14m), when compared to the anaplastic astrocytomas with score 2 DJ-1 which were associated with longer survival (32m) (Log rank = 17.6, P = 0.0001) (Figure 5b). This evidence concerns the gene PARK7 and astrocytoma (excluding glioblastoma).