IGF2 and neoplasm: Firstly, the use of our expression system was identified by EGFP reporter assays, and data demonstrated that green fluorescence was positive in HRT-18 and HT-29 tumor cell lines that was loss of imprinting of IGF2, but only weak expression observed in HCT-116 cells, MCF-7 cells and GES-1 cells that were maintenance of imprinting of IGF2 regardless of the multiplicity of infection or the prolonged infection time.