We further validated SLAMF7 expression by flow cytometric analysis, and confirmed that SLAMF7 was over-expressed in t(4;14) MM cell lines and reduced upon MMSET knockdown (Fig. 2B), while four of five non-t(4;14) MM cell lines expressed low level of SLAMF7 (Fig. 2B). Here, SLAMF7 is linked to Miyoshi myopathy.