TNF and chronic obstructive pulmonary disease: The observed phagocytic activity of the neutrophils fall on the background of the increasing phagocytic activity of neutrophils in patients with CB (TNF-α, s-TNFα-RI (p55)) and COPD (TNF-α, s-TNFα-RI (p55), TGF-β) indicates the development of the chronic inflammatory process [12].