We address MM because of the proliferation of publications, some scholarly, some in the popular press, that claim physical or psychological benefit from one or more of these practices, including reduced anxiety and depression, a more positive affective state, greater calmness of mind, greater physical relaxation, improved general health, better balance, lower blood pressure (BP), and improved biomarkers for inflammation and immune function [such as C-reactive protein (CRP) and cortisol] (7, , , , , –13). The gene discussed is CRP; the disease is major depressive disorder.