Finally, there is compelling evidence of mitochondrial dysfunction from in vivo imaging of double-transgenic mice with CFP-labeled mitochondria and YFP-labeled axoplasm (Thy1-MitoCFP × Thy1-YFP-16) induced with experimental autoimmune encephalomyelitis (EAE), a commonly used animal model for MS (Nikic et al., 2011). Here, THY1 is linked to myeloid sarcoma.