Jones et al. demonstrated that cyclin D3 is directed for proteasomal degradation by the GSK3β-mediated phosphorylation when GSK3β (glycogen synthase kinase 3β) is stabilised by an increased autophosphorylation in DM1 cells induced by the presence of “CUG” transcripts [46]. The gene discussed is GSK3B; the disease is myotonic dystrophy type 1.