ITGAM and cancer: Myeloid-derived suppressor cells (MDSCs), which are known to be CD11b+Gr-1+ in mice for example, have been demonstrated to undertake an immunosuppressive role in cancer, but monocytic MDSCs produce high levels of NO[10], which is reflective of characteristics displayed by the CD11b+Ly-6C-Ly-6G+ BMDMs in this study.