GFM1 and infection: In C. albicans, deleting EFG1, either alone or in combination with the transcription factor CPH1, results in greatly attenuated virulence in infection of mice (Lo et al., 1997), Caenorhabditis elegans (Pukkila-Worley et al., 2009), Drosophila (Chamilos et al., 2006) and zebrafish (Chao et al., 2010).