Correspondingly, the CEA assays performed in the present study showed no diagnostic value for ACA (AUC = 0.453), and also exhibited a lower sensitivity (38.96% vs. 70.13%) and accuracy (63.58% vs. 67.90%) for Duke’s stage A and B CRC, compared with kininogen-1. This evidence concerns the gene CEACAM5 and colorectal carcinoma.