When Duke’s stage C and D CRC patients were analyzed, the aforementioned five parameters for kininogen-1 were 72.73%, 65.88%, 62.34%, 75.68%, and 68.87%, respectively, and for CEA, were 34.85%, 85.88%, 65.71%, 62.93%, and 63.58%, respectively. The gene discussed is KNG1; the disease is colorectal carcinoma.