Moreover, the mean number of ultrasonography and AFP examinations were significantly higher in the IBT group compared with the non-treated group for all endpoints (hepatocellular carcinoma [Table S6-a], esophageal varices bleeding [Table S6-b], hepatic encephalopathy, [Table S6-c], ascites [Table S6-d], cirrhosis [Table S6-e], and any cirrhosis complication [Table S6-f]; All P<0.001). The gene discussed is AFP; the disease is Cirrhosis.