CST3 and cirrhosis of liver: Studies have also shown poor predictive value in various subgroups such as in ill and hospitalized patients [13], in liver cirrhosis [14], in obese patients [15], in diabetics with normal serum creatinine levels [16], etc. Efforts are therefore continuing to develop more accurate equations to have broader utility in diverse populations, and the latest is the development by the CKD-EPI collaboration of the serum creatinine based CKD-EPI equation, a serum Cystatin C based equation, and an equation based on a combination of both these parameters [9], [17], [18].