Consistent with mBAND-FISH data, RecQL4 band intensity and quantitative real-time PCR result in MDA-MB-231 was very similar to primary HMEC cells, whereas an enrichment of RecQL4 DNA was observed in MCF-10F and other four breast tumor cell lines (MCF-7, MDA-MB361, MDA-MB436 and MDA-MB453 cells, Fig. 1C). Here, RECQL4 is linked to breast neoplasm.