For example, the presence of specific ERAP1 SNPs have correlated with the presence of several pathological conditions such as the chronic inflammatory disorder ankylosing spondylitis (AS) [62], [63], type I diabetes (T1D) [64], multiple sclerosis (MS), Crohn’s disease (CD) [65], Behcet's disease [66] and hypertension [67]. This evidence concerns the gene ERAP1 and multiple sclerosis.