In a third experiment B-cells but not T-cells from donors immunized with TscFv clone S9/P2 were able to transfer protection from T1D induced by NtfrRII specific CD4+ T-cells and diabetes induction by BDC2.5 T-cells was prevented by B but not T-cells from donors vaccinated with BDC2.5 TscFv (Table 2, experiment C). This evidence concerns the gene CD4 and type 1 diabetes mellitus.