miR-155 has been shown to target SOCS1 in macrophages, positively regulating the host anti-viral response by promoting type I IFN signalling [21]; and in breast cancer cells, miR-155 suppression of SOCS1 plays an oncogenic role resulting in the constitutive activation of the JAK-STAT pathway [22]. This evidence concerns the gene SOCS1 and breast carcinoma.