Interestingly, miR-19a is induced by the anti-viral JAK-STAT signalling cytokine, IFN-α [29] and reduces SOCS1 expression, which may be linked to enhanced IL-6 signalling in multiple myeloma [30], suggesting a significant role for miR-19a in the regulation of the JAK-STAT pathway. The gene discussed is SOCS1; the disease is plasma cell myeloma.