We have previously found that the increased expression of P-cadherin promotes invasive effects in breast cancer cells, which can be, at least in part, attributed to the release of a soluble form of P-cadherin (sP-cad) to the extracellular media, that is capable by itself to cause invasion of E-cadherin positive, non-invasive, cell lines [6]. Here, CDH1 is linked to breast cancer.