In conclusion, our analysis of EGFR mutations in a homogenous group of 143 Caucasian patients with NSCLC demonstrates that activating EGFR mutations are present in 6.29 % of patients, and include exon 19 mutations (2.1 %) and exon 21 mutations (4.2 %). Here, EGFR is linked to non-small cell lung carcinoma.