Moreover, the mutations ALPK2.R136S, CHST9.S122N, FAM38B.V2463, LAMA1.S1577A, LAMA1.K2002E, MYOM1.T215M, SERPINB10.R246C and SLC14A2.A880T were found in all three tumor samples and shared a similar frequency profile. Here, ALPK2 is linked to neoplasm.