In addition, other genes have been related to tissue repair (elastin [ELN]) [22,23], muscle assembly and force transmission (titin [TTN]) [24], skeletal muscle regeneration (SRY-related HMG-box [SOX15]) [25], muscle damage (insulin-like growth factor 2 [IGF2]) [26], response to muscle damage (chemokine, CC motif, ligand 2 [CCL2]) [27], ligament ruptures ([COL1A1] and collagen type 5 alpha 1[COL5A1]) [28], and tendinopathy (COL5A1 and tenascin [TNC]) [10,29]. The gene discussed is TTN; the disease is disease of the tendon.