First, we enumerated apoptotic epitope-specific CD8+ T cells in the peripheral blood of 15 HLA-A2+ MS patients (providing adequate numbers of PBMCs to extend the analyses to dextramer staining), as compared with 10 HDs, by using dextramers of HLA-A*0201 molecules complexed to apoptotic (ACTB266-274, MYH9478-486, MYH9741-749, VIME78-87, or VIME225-233) peptides (Figure 2). This evidence concerns the gene CD8A and myeloid sarcoma.