F10 and thrombocytosis disease: These changes comprise different levels of blood coagulation abnormalities, such as shortened aPTT (activated partial thromboplastin time), elevated levels of circulating blood coagulation proteins [i.e., fibrinogen, FV (factor V), FVIII (factor VIII), FIX (factor IX) and FX (factor X)], thrombocytosis and increased concentrations of fibrin/fibrinogen degradation products, among others [14].