An analysis with the microarray GSE4290 dataset of two probe sets corresponding to the FOXP3 gene (221334_s _at and 224211_s_at) confirmed that the expression of FOXP3 is significantly down-regulated in 73 glioblastomas compared to 15 normal brains (P = 0.003 for 221334_s _at; P = 0.008 for 224211_s_at; Figure 2A). This evidence concerns the gene FOXP3 and glioblastoma.