Langerhans cell sarcoma (LCS) or mammary sarcoma (MS) may be similar to PES but immunohistochemistry, in the LCS the tumour cells are positive for CD1a, S-100 protein and langerin strongly and diffusely[29], while in MS CD10 and vimentin are positive diffusely whereas epithelial markers and other myoepithelial or myogenic markers were all negative[30]. This evidence concerns the gene MME and Langerhans cell sarcoma.