Immunohistochemistry the tumor was positive for vimentin, smooth muscle actin and Ki-67; focal positivity with AE1-AE3 CK, CK5 and high molecular weight cytokeratin and negative for EMA, CD34, desmin, myosin, CroA, synaptophysin and S100 (Figure 1C). The gene discussed is MYH14; the disease is neoplasm.