IFNB1 and infection: Although the in vivo data of enhanced IFN-β induction in the mouse lung (Figure 3b) appears to contradict the reduced IFN-β induction seen in mouse cells seen in Figure 3b, these findings are however consistent with the low level of human IFN-β induced by A/HK/156/1997 (H5N1) virus on infection of human A549 epithelium [78] versus the high IFN-β seen in humans infected with H5N1 viruses [79].