Compared with the control group, the level of GluN3A protein was increased to 133±3, 140±6, 158±7, 167±4, 156±5 and 149±5% (F=106.4, P<0.01, n=5) in the hippocampus, and to 105±3, 119±7, 133±7, 137±10, 135±7 and 132±1% in the prefrontal cortex (F=29.80, P<0.01, n=5) after 0.5, 1, 3, 6, 18 and 24 h of ischemia, respectively. Here, GRIN3A is linked to ischemia.