For example, coexpression of HERG and tumor necrosis factor receptor 1 (TNFR1) has been found at the cell membrane of SKBR3 and SH-SY5Y cell lines, and HERG appears to recruit TNFR1 to the membrane, therefore enhancing TNF-α-induced cancer cell proliferation (Wang et al., 2002). This evidence concerns the gene KCNH2 and cancer.