With respect to the clinical setting, Baeten et al. found increased CD68+ macrophages in tumor biopsy samples of rectal cancer patients after radiotherapy and Kioi et al. demonstrated an increase in CD11b+ myeloid cells in glioblastomas recurring after radiation (Baeten et al., 2006; Kioi et al., 2010). The gene discussed is ITGAM; the disease is glioblastoma.