TP53 and lung cancer: Radon measurements were performed on the homes that each individual had occupied for at least 1 year during the preceding 30 years [74] and although the authors identified a TP53 mutation difference between lung cancers from smokers and non- or ex-smokers (most visibly a lower mutation frequency in non-smokers compared to smokers), they found no statistically significant relationship with TP53 mutations and radon exposure.