Figure 2C shows that treatments with EPA significantly decreased (p<0.05) the number of CD133 (−) cells (bulk of tumor), at the physiologic concentration of 25 uM. Interestingly, the CD133 (+) CSLCs population was only barely affected by the same concentration of EPA (25 uM) that caused a reduction in cell number of the CD133 (−) sub-population. The treatment with SA, which is a saturated fatty acid, did not significantly change either CD133 (+) or CD133 (−) cell number (figure 2D). Here, PROM1 is linked to neoplasm.