To show that S100A8/A9 levels generally correlated with hyperphosphorylation of p-Cdc2 (Thr14/Tyr15) in HNSCC, we tested three additional HNSCC cell lines with varying endogenous S100A8/A9 expression levels. The gene discussed is IGKV1D-22; the disease is head and neck squamous cell carcinoma.