ICAM1 and diabetes mellitus: Diabetes causes a variety of physiologic and molecular abnormalities in the retina that have been grouped together as indicating a local inflammation [1], including increases in expression or activity of NF-ĸß, IL-1ß, TNFα, RAGE, iNOS, ICAM-1, and p38 MAPK, as well as increases in leukostasis and accumulation of albumin in the neural retina.