VEGFC and neoplasm: To test if VEGF family members contribute to the up-regulation of lymph transport associated with disease progression, we dosed C6 tail xenograft tumor-bearing animals with function blocking antibodies to NRP2 [35], called anti-NRP2B herein, VEGF-C (clone VC4.5 [Caunt et al, in preparation] or VC1.12, Figure S2), or VEGF-A [45] weekly beginning two days after xenograft implant.