A defect in the ability of Glut4 in muscle and fat cells to appropriately translocate to the cell surface in response to elevated circulating insulin levels is the proximal cause of peripheral insulin resistance [6], [7], a pathological state that is associated with obesity, metabolic syndrome, and type 2 diabetes mellitus [8], [9], [10], [11]. Here, SLC2A4 is linked to Insulin resistance.