Both IL-17A and IL-22 have been shown to be pro-inflammatory cytokines that participate in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis (RA) [11], Crohn’s disease [12], systemic lupus erythematosus (SLE) [13], and psoriasis [14]. The gene discussed is IL22; the disease is systemic lupus erythematosus.