High levels of the pro-inflammatory cytokines such as interleukin 1 beta (IL-1 beta), interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF alpha), were detected in the cerebro-spinal fluid (CSF) of patients with meningitis, which is typical of the severe inflammation of the brain [4]. The gene discussed is TNF; the disease is meningitis.