PIN1 and cancer: Consistent with results from genotype data, the −842 C allele of PIN1 was associated with reduced susceptibility to cancer in all three comparisons (homozygote comparison, heterozygote comparison and dominant model), especially in homozygote comparison (CC vs. GG, OR = 0.589, 95% CI:0.394–0.880, Pheterogeneity = 0.885; Figure 3), in which no significant association was observed when estimated by genotype distribution data.