Mutation G14459A (MT-ND6 gene) results in alanine to valine substitution in a conserved region of ND6 protein at position 72, and is associated with hereditary ocular neuropathy, atrophy of visual nerve, Leber’s hereditary visual neuropathy, dysfunction of basal ganglia, musculospastic syndrome and encephalopathy [13], [29]–[31]. This evidence concerns the gene MT-ND6 and Encephalopathy.