These cells also revealed a specific expression of HPV16 E6 and E7 which was corroborated with high STAT3 and pSTAT3 expression, whereas E6 and E7 expression was completely absent in HPV negative C33a cells thus confirming specific binding of the antibody to respective proteins and indicated existence of a potential association between expression and activation of STAT3 and E6/E7 expression in cervical cancer cell lines (Fig. 1A). This evidence concerns the gene STAT3 and cervical carcinoma.