In mice, several examples of strain-specific kidney disease have been described in which the C57BL/6 strain is generally resistant to experimental glomerular disease, whereas the BALB/c and FVB strains are sensitive to glomerular disease including Adriamycin nephropathy [20], HIV-nephropathy [21], puromycin aminonucleoside [22], the tetraspannin mutant CD151 [23] and others. The gene discussed is CD151; the disease is glomerular disorder.