The absence of an effect on Tg26 nephropathy from heterozygous loss of Myh9 in this previous study is consistent with the reports that mice with one copy of this null allele had either a very subtle phenotype of sensorineural hearing loss or no phenotype at all, leading to the conclusion that the Myh9 locus is not haploinsufficient [41], [42]. This evidence concerns the gene MYH9 and Nephropathy.