A second form of kidney disease attributed to MYH9 is a possible predisposition to common forms of kidney disease, an idea that arose from initial reports that MYH9 polymorphisms in several introns that comprise the E1, F1 and S1 haplotypes of MYH9 are associated with both primary and HIV-related glomerulosclerosis, non-diabetic ESRD, and hypertensive nephrosclerosis in African-Americans and Hispanic-Americans [4]–[7]. Here, MYH9 is linked to kidney disorder.