MYH9 and focal segmental glomerulosclerosis: The foremost is a rare, autosomal dominant form of focal and segmental glomerulosclerosis (FSGS) due to “MYH9-related disease,” a term uniting four previously distinct Giant Platelet Syndromes: May-Hegglin Anomaly, Sebastian Syndrome, Epstein's Syndrome and Fetchner's Syndrome, all of which result from dominant mutations in MYH9[1].