Previously, lysosome related genes, such as SLC11A1 (encoding solute carrier family 11 member 1, a lysosome membrane protein) [36] and IRGM (encoding immunity-related GTPase family M, mediating fusion of M. tuberculosis-contained endosome with lysosome) [37], were proven to be associated with TB susceptibility. Here, SLC11A1 is linked to tuberculosis.