We have discovered ATP6V1C1, MYBBP1A, MACF1 and MYO10 upregulation in lung adenocarcinoma and accordingly, it is concluded that these genes have an important role in lung adenocarcinoma metastasis and we have reported all the mentioned genes for the first time in lung adenocarcinoma. Here, ATP6V1C1 is linked to lung adenocarcinoma.