Working on the premise that pTregs and conventional T cells share the same TCRs, we used a mouse model of carcinogen-induced tumors to compare the TCR repertoires of tumor-infiltrating Foxp3− and Foxp3+CD4+ T cells in order to determine the extent of TCR overlap between the two populations following their recovery from the tumor microenvironment (15). Here, FOXP3 is linked to neoplasm.