DACH1 and cancer: As many of the eye/antennal disc transcription factors targeted by Ab have human orthologues that are also implicated in cell fate regulation, organogenesis and tumourigenesis (eg. Hth (MEIS family), Dac (DACH family), Eya (EYA family), Dll (DLX family)), it is likely that this work will promote a deeper understanding of how cell fate control also influences the formation of human cancers.