Whilst some were repressed by expression of Ab alone, most of these were substantially further repressed in combination with the absence of scrib. Potential direct targets of Ab involved in regulating cell fate in the eye/antennal disc, and repressed in the tumour state, included dan, eyg el, h and noc (Class 1), hth, dac, eya, bab2, pnr, ss (Class 2), and da (Class 4). This evidence concerns the gene SCRIB and neoplasm.