MAPK8 and neoplasm: The expression array of scrib−+ab tumours indicated that JNK signalling was also likely to be active within these tumours, as evidenced by the upregulation of known JNK-regulated genes such as Matrix metalloproteinase 1 (Mmp1) and scarface (scaf) [32], [34], which were also identified as potential Ab targets (Class 1 and 2, respectively).