In order to assess the effect of NTRK3 on colorectal cancer, NTRK3 was transfected into the HCT116 (MSI), RKO (CIMP) and HT29 (CIMP/MSS) cell lines, which lack NTRK3 and NT3 mRNA expression (Figure S3A and B). The gene discussed is NTRK3; the disease is colorectal cancer.