In light of the prior reports implicating a fusion gene involving NTRK3 affecting TGF-β signaling and TGF-β mediated cell behavior, we also assessed the TGF-β, BMP signaling and EMT markers in colon cancer cells after transfection with NTRK3[4], [5]. The gene discussed is NTRK3; the disease is malignant colon neoplasm.