Because major cell types known to produce IFN-I after viral infection in vivo are pDCs, conventional DCs (cDCs) including myeloid DCs (mDCs) and lymphoid DCs (lDCs), and Macs [35], we sorted these IFN-I-producing cell types and, as a negative control, polymorphonuclear cells (PMNs) and monocytes (Mos) from splenocytes of WT and Oasl1 KO mice at 2 d p.i. (Fig. S9), followed by measurement of their IFN-I gene expression levels. The gene discussed is OASL; the disease is viral infectious disease.