Analysis of LD in the unrelated individuals from the Croatian data set showed that the minor allele (A) of CFH SNP rs6677604 was only weakly correlated with the minor alleles of two non-synonymous SNPs that have previously been associated with AMD risk, in exon 2 [rs800292 (I62V), T-allele, r2 = 0.04] (28) and exon 9 [rs1061170 (Y402H) C-allele, r2 = 0.16] (20–22). The gene discussed is CFH; the disease is age-related macular degeneration.