CFH and age-related macular degeneration: The CNP147 deletion was in LD with CFH-raising alleles at rs6677604 (r2 = 0.84) and rs2274700 (r2 = 0.33), a synonymous coding SNP (A473A) in exon 10 of CFH (24), both of which are located within a 32 kb region of the CFH gene that shows the strongest association with AMD (23–25).